Bob Saget, the actor-comedian known for his role as beloved single dad Danny Tanner on the sitcom Full House and as the wisecracking host of America’s Funniest Home Videos, died while on a stand-up tour. He was 65.

Deputies in Orange County, Florida, were called Sunday about an “unresponsive man” in a hotel room at the Ritz-Carlton in Orlando and found Saget dead, according to a sheriff’s statement on Twitter. Detectives found “no signs of foul play or drug use in this case.”

Saget was in Florida as part of his “I Don’t Do Negative Comedy Tour.” After warm audience receptions to his gigs Friday in Orlando and Saturday in the Ponte Vedra Beach resort area, he celebrated online.